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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC18A3
All Species:
9.39
Human Site:
T74
Identified Species:
18.79
UniProt:
Q16572
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16572
NP_003046.2
532
56961
T74
G
G
E
G
P
T
R
T
P
E
V
W
E
P
T
Chimpanzee
Pan troglodytes
XP_001138996
532
56986
T74
G
G
E
G
P
T
R
T
P
E
V
W
E
P
T
Rhesus Macaque
Macaca mulatta
XP_001107292
532
57072
T74
G
G
E
G
P
T
R
T
P
E
V
W
E
P
T
Dog
Lupus familis
XP_543901
528
56326
D70
V
I
V
P
I
V
P
D
Y
I
A
G
M
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
O35304
530
56597
I74
G
S
E
S
P
T
L
I
S
E
V
W
E
P
T
Rat
Rattus norvegicus
Q62666
530
56519
V74
G
S
E
G
P
T
L
V
S
E
V
W
E
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_996865
522
55424
Y57
L
L
L
D
N
M
L
Y
M
V
I
V
P
I
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P59845
493
53034
L42
E
R
K
R
R
L
L
L
V
V
V
C
V
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O17444
578
64295
P73
F
D
D
G
P
T
P
P
P
L
R
D
N
I
T
Honey Bee
Apis mellifera
XP_624140
581
64261
D71
F
G
D
V
E
E
E
D
E
V
N
A
T
G
T
Nematode Worm
Caenorhab. elegans
P34711
532
58625
K57
V
I
V
P
I
I
P
K
Y
L
R
D
I
H
N
Sea Urchin
Strong. purpuratus
XP_782213
561
61607
I58
Y
M
V
I
V
P
I
I
P
D
Y
L
R
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.3
87.7
N.A.
93.8
94.1
N.A.
N.A.
66.5
N.A.
66.7
N.A.
46.7
49
45.2
51.1
Protein Similarity:
100
99.2
99
90
N.A.
94.5
94.9
N.A.
N.A.
78
N.A.
76.5
N.A.
61.5
62.8
59.7
67.2
P-Site Identity:
100
100
100
0
N.A.
66.6
73.3
N.A.
N.A.
0
N.A.
6.6
N.A.
33.3
13.3
0
6.6
P-Site Similarity:
100
100
100
0
N.A.
66.6
73.3
N.A.
N.A.
6.6
N.A.
13.3
N.A.
40
20
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
9
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
9
17
9
0
0
0
17
0
9
0
17
0
0
0
% D
% Glu:
9
0
42
0
9
9
9
0
9
42
0
0
42
0
0
% E
% Phe:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
42
34
0
42
0
0
0
0
0
0
0
9
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
17
0
9
17
9
9
17
0
9
9
0
9
17
17
% I
% Lys:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
9
% K
% Leu:
9
9
9
0
0
9
34
9
0
17
0
9
0
0
9
% L
% Met:
0
9
0
0
0
9
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
9
0
9
0
9
% N
% Pro:
0
0
0
17
50
9
25
9
42
0
0
0
9
42
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
9
0
9
9
0
25
0
0
0
17
0
9
0
0
% R
% Ser:
0
17
0
9
0
0
0
0
17
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
50
0
25
0
0
0
0
9
0
59
% T
% Val:
17
0
25
9
9
9
0
9
9
25
50
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
9
17
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _